Current Open RFP

GHIT Fund RFP Hit-to-Lead Platform 2018-002

The Hit-to-Lead Platform (HTLP) is designed to leverage medicinal chemistry expertise in Japan and facilitate access to Japanese companies or academic organizations’ relevant and diverse compounds for drugs development to address malaria, tuberculosis, Chagas disease, and Visceral leishmaniasis.

 

HTLP projects will focus on the aspect of the drug discovery and development process that progresses hits, identified through compound library screening, into lead compounds that can then be optimized into drug candidates. This platform will provide a bridge from early drug discovery to our product development platform that begins with the lead-optimization step.

 

The key requirement of the Hit-to-Lead Platform is to convert drug hits originated from Japanese compound libraries into lead series through a comprehensive assessment of chemical integrity, synthetic accessibility, scalability and novelty, functional behavior, and structure-activity relationships (SAR), as well as bio-physiochemical and absorption, distribution, metabolism and excretion (ADME) properties.

 

Interested applicants can find detailed information on the RFP and the Intent to Apply (ITA) form below. An ITA should be submitted first and upon an eligibility assessment, approved applicants will be notified and request to submit a full proposal to the GHIT Fund.

RFP and Intent to Apply

GHIT-RFP-HTLP-2018-002
GHIT-RFP-HTLP-2018-002 IntentToApply

Key RFP Milestone Dates

RFP Release	August 1, 2018
Intent to Apply	No later than 10:00 am Tokyo time on September 3, 2018 Submit Intent to Apply form to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-002_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on September 26, 2018 Submit questions to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-002_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on October 3, 2018 Submit proposal to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-002_Proposal
Proposals Evaluation and Interview Processes	October 2018 - February 2019
Award Notification to All Applicants	February 2019
Investment Agreement Fully Executed (Awarded Proposals)	March 2019

Past RFP

GHIT Fund RFP Hit-to-Lead Platform 2018-001

The Hit-to-Lead Platform (HTLP) is designed to leverage medicinal chemistry expertise in Japan and facilitate access to Japanese companies or academic organizations’ relevant and diverse compounds for drugs development to address malaria, tuberculosis, Chagas disease, and Visceral leishmaniasis.

 

HTLP projects will focus on the aspect of the drug discovery and development process that progresses hits, identified through compound library screening, into lead compounds that can then be optimized into drug candidates. This platform will provide a bridge from early drug discovery to our product development platform that begins with the lead-optimization step.

The key requirement of the Hit-to-Lead Platform is to convert drug hits originated from Japanese compound libraries into lead series through a comprehensive assessment of chemical integrity, synthetic accessibility, scalability and novelty, functional behavior, and structure-activity relationships (SAR), as well as bio-physiochemical and absorption, distribution, metabolism and excretion (ADME) properties.

 

Interested applicants can find detailed information on the RFP and the Intent to Apply (ITA) form below. An ITA should be submitted first and upon an eligibility assessment, approved applicants will be notified and request to submit a full proposal to the GHIT Fund.

RFP and Intent to Apply

GHIT-RFP-HTLP-2018-001
GHIT-RFP-HTLP-2018-001 IntentToApply

Key RFP Milestone Dates

RFP Release	June 8, 2018
Intent to Apply	No later than 10:00 am Tokyo time on June 15, 2018 Submit Intent to Apply form to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-001_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on June 22, 2018 Submit questions to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-001_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on June 29, 2018 Submit proposal to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2018-001_Proposal
Proposals Evaluation and Interview Processes	July 2018
Award Notification to All Applicants	July 2018
Investment Agreement Fully Executed (Awarded Proposals)	August 2018

GHIT Fund RFP Hit-to-Lead Platform 2017-001

The Hit-to-Lead Platform (HTLP) is designed to leverage medicinal chemistry expertise in Japan and facilitate access to Japanese companies or academic organizations’ relevant and diverse compounds for drugs development to address malaria, tuberculosis, Chagas disease, and Visceral leishmaniasis.

 

HTLP projects will focus on the aspect of the drug discovery and development process that progresses hits, identified through compound library screening, into lead compounds that can then be optimized into drug candidates. This platform will provide a bridge from early drug discovery to our product development platform that begins with the lead-optimization step.

 

The key requirement of the Hit-to-Lead Platform is to convert drug hits originated from Japanese compound libraries into lead series through a comprehensive assessment of chemical integrity, synthetic accessibility, scalability and novelty, functional behavior, and structure-activity relationships (SAR), as well as bio-physiochemical and absorption, distribution, metabolism and excretion (ADME) properties.

 

Interested applicants can find detailed information on the RFP and the Intent to Apply (ITA) form below. An ITA should be submitted first and upon an eligibility assessment, approved applicants will be notified and request to submit a full proposal to the GHIT Fund.

RFP and Intent to Apply

GHIT-RFP-HTLP-2017-001
GHIT-RFP-HTLP-2017-001 IntentToApply

Key RFP Milestone Dates

RFP Release	July 25, 2017
Intent to Apply	No later than 10:00 am Tokyo time on September 1, 2017 Submit Intent to Apply form to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2017-001_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on September 20, 2017 Submit questions to HTLPResponse@ghitfund.org Email Subject Line: GHIT-RFP-HTLP-2017-001_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on October 2, 2017 Submit proposal to HTLPResponse@ghitfund.org  Email Subject Line: GHIT-RFP-HTLP-2017-001_Proposal
Proposals Evaluation and Interview Processes	October 2017 - January 2018
Award Notification to All Applicants	February 2018
Investment Agreement Fully Executed (Awarded Proposals)	March 2018

GHIT Fund RFP Hit-to-Lead Platform 2016-002

The Hit-to-Lead Platform (HTLP) is designed to leverage medicinal chemistry expertise in Japan and facilitate access to Japanese companies or academic organizations’ relevant and diverse compounds for drugs development to address malaria, tuberculosis, Chagas disease, and Visceral leishmaniasis.

 

HTLP projects will focus on the aspect of the drug discovery and development process that progresses hits, identified through compound library screening, into lead compounds that can then be optimized into drug candidates. This platform will provide a bridge from early drug discovery to our product development platform that begins with the lead-optimization step.

 

The key requirement of the Hit-to-Lead Platform is to convert drug hits originated from Japanese compound libraries into lead series through a comprehensive assessment of chemical integrity, synthetic accessibility, scalability and novelty, functional behavior, and structure-activity relationships (SAR), as well as bio-physiochemical and absorption, distribution, metabolism and excretion (ADME) properties.

 

Interested applicants can find detailed information on the RFP and the Intent to Apply (ITA) form below.  An ITA should be submitted first and upon an eligibility assessment, approved applicants will be notified and request to submit a full proposal to the GHIT Fund.

RFP and Intent to Apply

GHIT-RFP-HTLP-2016-002
GHIT-RFP-HTLP-2016-002 IntentToApply

Key RFP Milestone Dates

RFP Release	August 1, 2016
Intent to Apply	No later than 10:00 am Tokyo time on September 1, 2016   Submit Intent to Apply form to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2016-002_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on September 20, 2016   Submit RFP questions to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2016-002_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on October 3, 2016   Submit proposal to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2016-002_Proposal
Proposals Evaluation and Interview Processes	October 2016 - January 2017
Award Notification to All Applicants	No later than February 1, 2017
Investment Agreement Fully Executed (Awarded Proposals)	No later than March 31, 2017

GHIT Fund RFP Hit-to-Lead Platform 2016-001

The GHIT Fund endeavors to further facilitate collaboration & funding of global health technology R&D, to build momentum, and to demonstrate action and results. The Hit-to-Lead Platform (HTLP) is designed to leverage the Product Development Partnerships (PDPs)’ active platform for neglected and tropical diseases in partnership with Japanese companies or academic organizations that have relevant compounds. The intention is to facilitate access to the chemical diversity in Japanese research organizations and to the medicinal chemistry expertise in Japan.

 

If you are interested in applying for the platform, please see RFP.

RFP and Intent to Apply

GHIT-RFP-HTLP-2016-001
GHIT-RFP-HTLP-2016-001 IntentToApply

Key RFP Milestone Dates

RFP Release	February 26, 2016
Intent to Apply	No later than 10:00 am Tokyo time on March 28, 2016   Submit Intent to Apply form to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2016-001_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on April 18, 2016   Submit questions to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2016-001_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on April 27, 2016   Submit proposal to HTLPResponse@ghitfund.org Email   Subject Line: GHIT-RFP-HTLP-2016-001_Proposal
Award Notification to All Applicants	No later than August 1, 2016

GHIT Fund RFP Hit-to-Lead Platform 2015-002

The GHIT Fund endeavors to further facilitate collaboration & funding of global health technology R&D, to build momentum, and to demonstrate action and results. The Hit-to-Lead Platform (HTLP) is designed to leverage the Product Development Partnerships (PDPs)’ active platform for neglected and tropical diseases in partnership with Japanese companies or academic organizations that have relevant compounds. The intention is to facilitate access to the chemical diversity in Japanese research organizations and to the medicinal chemistry expertise in Japan.

 

If you are interested in applying for the platform, please see RFP.

RFP and Intent to Apply

GHIT-RFP-HTLP-2015-002 IntentToApply
GHIT-RFP-HTLP-2015-002
Results for RFP-HTLP-2015-002

Key RFP Milestone Dates

RFP Release	August 12, 2015
Intent to Apply	No later than 10:00 am Tokyo time on October 5, 2015   Submit Intent to Apply form to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-002_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on November 2, 2015   Submit questions to  HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-002_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on November 9, 2015   Submit questions to  HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-002_Proposal
Award Notification to All Applicants	No later than February 1, 2016   Investment Agreement :No later than March 1, 2016

GHIT Fund RFP Hit-to-Lead Platform 2015-001

The GHIT Fund endeavors to further facilitate collaboration & funding of global health technology R&D, to build momentum, and to demonstrate action and results. The Hit-to-Lead Platform (HTLP) is designed to leverage the Product Development Partnerships (PDPs)’ active platform for neglected and tropical diseases in partnership with Japanese companies or academic organizations that have relevant compounds. The intention is to facilitate access to the chemical diversity in Japanese research organizations and to the medicinal chemistry expertise in Japan.

 

If you are interested in applying for the platform, please see RFP.

RFP and Intent to Apply

GHIT-RFP-HTLP-2015-001
GHIT-RFP-HTLP-2015-001 IntentToApply
Results for RFP-HTLP-2015-001

Key RFP Milestone Dates

RFP Release	February 6, 2015
Intent to Apply	No later than 10:00 am Tokyo time on March 20, 2015   Submit Intent to Apply form to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-001_Intent to Apply
Q&A	No later than 10:00 am Tokyo time on April 13, 2015   Submit questions to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-001_Questions
Full Proposal Due	No later than 10:00 am Tokyo time on April 20, 2015   Submit proposal to HTLPResponse@ghitfund.org   Email Subject Line: GHIT-RFP-HTLP-2015-001_Proposal
Award Notification to All Applicants	No later than August 1, 2015

GHIT Fund RFP Hit-to-Lead Platform 2014-002

The GHIT Fund endeavors to further facilitate collaboration & funding of global health technology R&D, to build momentum, and to demonstrate action and results. The Hit-to-Lead Platform (HTLP) is designed to leverage the Product Development Partnerships (PDPs)’ active platform for neglected and tropical diseases in partnership with Japanese companies or academic organizations that have relevant compounds. The intention is to facilitate access to the chemical diversity in Japanese research organizations and to the medicinal chemistry expertise in Japan.

RFP and Intent to Apply

GHIT Fund HTLP RFP2014-002
GHIT Fund HTLP RFP2014-002 Intent To Apply
Results for RFP-HTLP-2014-002

Key RFP Milestone Dates

RFP Release	August 6, 2014
Intent to Apply	10:00 am September 10, 2014 Submit GHIT_HTLP_RFP2014-002_Intent_To_Apply.docx to HTLPResponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-002 Intent to Apply
Q&A	Submit Questions to HTLPResponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-002 Questions
Full Proposal Due	10:00 am Tokyo Time October 10, 2014 Submit GHIT Fund HTLP Proposal, Timeline and Budget templates to HTLPResponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-002 Proposal
Award Notification to All Applicants	No later than January 31, 2015

GHIT Fund RFP Hit-to-Lead Platform 2014-001

The GHIT Fund endeavors to further facilitate collaboration & funding of global health technology R&D, to build momentum, and to demonstrate action and results. The Hit-to-Lead Platform (HTLP) is designed to leverage the Product Development Partnerships (PDPs)’ active platform for neglected and tropical diseases in partnership with Japanese companies or academic organizations that have relevant compounds. The intention is to facilitate access to the chemical diversity in Japanese research organizations and to the medicinal chemistry expertise in Japan.

RFP and Intent to Apply

GHIT Fund HTLP RFP 2014-001
GHIT Fund HTLP RFP2014-001 Intent To Apply
Results for RFP-HTLP-2014-001

Key RFP Milestone Dates

RFP Release	March 17, 2014
Intent to Apply	10:00 am April 04, 2014 Submit GHIT Fund HTLP RFP2014-001 Intent To Apply to HTLPresponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-001 Intent to Apply
Q&A	Submit Questions to HTLPresponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-001 Questions
Full Proposal Due	10:00 am Tokyo Time April 30, 2014 Submit GHIT Fund HTLP RFP2014-001 to HTLPresponse@ghitfund.org Email Subject Line: GHIT-HTLP_RFP-2014-001 Proposal
Award Notification to All Applicants	No later than July 15, 2014