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NTDpedia Your Guide to Neglected Tropical Diseases NTDpedia Your Guide to Neglected Tropical Diseases
Your Guide to
Neglected Tropical Diseases
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Sustainable Development Goal (SDG) 3: Ensure healthy lives and promote well-being for all at all ages

The SDGs were adopted at the United Nations Summit in September 2015 as part of a global agenda for a better future. Guided by the principle of “leaving no one behind,” the SDGs consist of 17 goals and 169 targets to be achieved by 2030. Among these, Goal 3 (Ensure healthy lives and promote well-being for all at all ages) aims to create a world where everyone can live a healthy and secure life. One of its key targets is to end the epidemics of major communicable diseases such as AIDS, tuberculosis, malaria, and neglected tropical diseases (NTDs), and combat hepatitis, water-borne diseases, and other communicable diseases.

To achieve global health equity, it is essential to understand and address NTDs, which continue to affect millions of people worldwide.

What are neglected tropical diseases (NTDs)?

NTDs are a group of 21 infectious diseases, including lymphatic filariasis, schistosomiasis, and dengue, that collectively affect approximately 1.5 billion people worldwide. These diseases are concentrated in poor regions of low- and middle-income countries and have a profound impact on people’s health and livelihoods. Despite the urgent need for medicines, vaccines, and diagnostic tools, research and development in this field are lagging due to limited funding and resources.

Vicious cycle of infectious diseases

Infectious diseases often trap people in a vicious cycle in which poverty drives illness, and illness deepens poverty.
In poor regions, lack of access to safe water and sanitation makes infections more likely. Limited healthcare access due to distance, cost, or infrastructure means that diseases often go untreated until they become severe.

As a result, people miss school or work, reducing income opportunities. This in turn limits access to nutritious food and clean living conditions, which again increases vulnerability to disease. Moreover, those left with long-term disabilities from infection often face stigma and discrimination, further excluding them from education and employment.

vicious_cycle virtuous_cycle

Breaking this cycle requires improving access to clean water and sanitation, strengthening healthcare systems, promoting early diagnosis and treatment, fostering education and understanding, reducing stigma, and improving living conditions to support social and economic development.

The 21 NTDs - Start by getting to know them

The World Health Organization (WHO) has designated 21 diseases as NTDs, conditions that humanity must overcome together. This list has expanded over time to include diseases such as snakebite envenoming and noma. These diseases are caused by various pathogens, including viruses, bacteria, parasites, and fungi. They are concentrated in tropical and subtropical regions, particularly in areas affected by poverty, where they continue to be overlooked in research and public health initiatives.

*To provide a better understanding of the condition, this page features detailed clinical photographs.
As some of these medical images may be visually intense, please proceed with caution based on your own comfort level.

© Shota Koyano

Editorial Supervisors: Prof. Kenji Hirayama, MD, Ph.D.
Professor, School of Tropical Medicine and Global Health
Dean, Interfaculty Initiative in Planetary Health
Nagasaki University

* This page is a general overview for non-specialist readers. Estimates for NTDs can differ between sources and may change as new data become available. Last reviewed: May, 2026.

The GHIT Fund is an international organization that provides funding for research and development of drugs, vaccines, and diagnostics for NTDs.

The greatest barrier to ending NTDs is not just the lack of medical tools, but lack of awareness and societal apathy. NTDpedia was built to transform a distant problem into something people can understand and then care about, which is the first step toward meaningful global action. The GHIT Fund envisions NTDpedia becoming a resource for anyone curious about these diseases, from students and teachers to companies and advocates. Apathy often reflects unfamiliarity rather than indifference. By making these diseases visible and understandable, GHIT aims to build the public support that drives investment in research and development for drugs, vaccines, and diagnostics for NTDs.